HTTP 404.2 Error ISAPI/CGI Restrictions Stopping .NET Framework 4.5.1
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Error
An HTTP 404.2 error code is received when ISAPI/CGI Restrictions are preventing the.NET Framework 4.5.1 from running.
Resolution
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Open Internet Information Services.
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Select the Server in the left tree view.
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In the IIS section, open ISAPI and CGI Restrictions.
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For all items beginning with ASP.NET v4.0, right-click the item and select Allow.